Biography
She has worked at UCSF to develop interdisciplinary teams of clinicians and researchers to bring the best care to patients and find the best platform to integrate translational research and improve the delivery of breast cancer care. In 2005, she received the NCI SPORE Investigator of the Year Award, an internationally recognized honor and designation.
She is the Principal Investigator of the I-SPY TRIAL program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design.
Dr. Esserman launched a University of California-wide breast cancer initiative called the Athena Breast Health Network, a project designed to follow 400,000 women from screening through treatment and outcomes, incorporating the latest in molecular testing and web-based tools into the course of care.
Dr. Esserman is nationally and internationally known as a leader in the field of breast cancer and has published over 200 articles in peer-reviewed journals covering all aspects of breast health including information systems, immunology, decision making, health policy and the use of imaging. She speaks extensively at public and private forums within the U.S. and internationally. Overall, Dr. Esserman's research and writing tends to focus on the goal of giving patients better access to accurate information so that they can become partners in their health care.
She was a member of President Obama’s Council of Advisors on Science and Technology (PCAST) Working Group on Advancing Innovation in Drug Development and Evaluation, which studied how the federal government can best support science-based innovation in the process of drug development and regulatory evaluation. In addition, she was a contributing member of a “taskforce” for President Obama’s Council of Advisors on Science and Technology.
Dr. Esserman received her Bachelor's degree in History of Science from Harvard University and completed her M.D. at Stanford University. She completed her surgery residency and oncology fellowship at Stanford University Medical Center. After her training, she joined the faculty at Stanford and received a Hartford fellowship to attend Stanford Business School where she received her M.B.A. in 1993. She then joined the faculty at the University of California, San Francisco.
Education
1974-77, Harvard University, A.B.
1978-83, Stanford University, M.D.
1983-85, Stanford University School of Medicine, Resident, General Surgery
1988-90, Stanford University School of Medicine, Resident, General Surgery
1990-91, Stanford University School of Medicine, Chief Resident, General Surgery
1985-88, Stanford University School of Medicine, Postdoctoral Fe, Oncology, Medical
1991-93, Stanford University, M.B.A.
Board Certifications
American Board of Surgery - General Surgery - 1992
Collaboration Interests
I am interested in:
- PolicyChange
Clinical Expertise
DCIS (Ductal Carcinoma in situ)
Inflammatory Breast Cancer
Invasive Breast Cancer
LCIS (Lobular Carcinoma in situ)
Lumpectomy/Partial Mastectomy
Lymphadenectomy
Mastectomy
Recurrent Breast Cancer
Sentinel Lymph Node Biopsy
Wire Localization Surgery
Clinical Trials
- MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles (NCT03053193)Related Conditions: Breast Cancer| Start Date: | End Date:
- DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment (NCT06075953)Related Conditions: Ductal Carcinoma in Situ, Breast Cancer, Carcinoma| Start Date: | End Date:
- Related Conditions: COVID-19| Start Date: | End Date:
- Related Conditions: Breast Cancer, Menopause| Start Date: | End Date:
- Related Conditions: Breast Cancer, Cancer, General| Start Date: | End Date:
- Related Conditions: Carcinoma, Intraductal, Noninfiltrating, Immunotherapy, Carcinoma| Start Date: | End Date:
- Related Conditions: Breast Cancer, Carcinoma| Start Date: | End Date:
- Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery (NCT00033397)Related Conditions: Breast Cancer| Start Date: | End Date:
- Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer (NCT00416403)Related Conditions: Breast Cancer, Carcinoma| Start Date: | End Date:
- Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction (NCT01258296)Related Conditions: Postoperative Pain| Start Date: | End Date:
- Related Conditions: Breast Cancer| Start Date: | End Date:
- Statins and Breast Cancer Biomarkers (NCT00914017)Related Conditions: Breast Cancer| Start Date:
Program Affiliations
- UCSF Center of Excellence for Breast Cancer Care
- UCSF Breast Care Center
- UCSF Helen Diller Comprehensive Cancer Center
Translational Co-Lead: Dr. Laura Esserman, is internationally recognized for her leadership of the ground-breaking I-SPY2 clinical trial and as an advocate for de-escalation of treatment for DCIS, and the initiation of the virtual preference pragmatic personalized screening trial (WISDOM) seeking to personalize the approach to screening. Her work in breast cancer spans the spectrum from public policy issues to basic science and the impact of both on the delivery of clinical care. Dr. Esserman has mentored 36 post-doctoral or clinical fellows during her career. She developed and runs a post-baccalaureate program that has trained 123 students over the past 15 years, most of whom have gone on to careers in medicine.
Dr. Esserman’s broad research interests provide exceptional opportunities for multidisciplinary training across the three themes, through clinical trials and biomarker studies on screening, prevention and treatment of breast cancer, many of which focus on improving healthcare value. Another fundamental and scalable effort is the implementation of systems to integrate care and research.
Grants and Funding
- Surgical Oncology Training Grant | NIH | 2020-07-15 - 2025-06-30 | Role: Principal Investigator
- Extending the Diversity, Reach, and Generalizability of the WISDOM Study | NIH | 2020-03-01 - 2025-02-28 | Role: Principal Investigator
- I-SPY2 +: Evolving the I-SPY 2 TRIAL to include MRI-directed, adaptive sequential treatment to optimize breast cancer outcomes | NIH | 2017-09-08 - 2022-08-31 | Role: Principal Investigator
- Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancers | NIH | 2015-09-16 - 2021-08-31 | Role: Principal Investigator
- Modeling the Impact of Targeted Therapy Based on Breast Cancer Subtypes | NIH | 2014-09-18 - 2020-08-31 | Role: Principal Investigator
- Integrated Biomarkers to Characterize Breast Cancer Risk | NIH | 2004-09-20 - 2011-06-30 | Role: Principal Investigator
Research Interests
- BRCA1 Protein
- BRCA2 Protein
- Breast Diseases
- Breast Neoplasms
- Male
- Mastectomy
- Segmental
- Ultrasonography
- Mammary
- Cancer Vaccines
- Genes
- Tumor Suppressor
- Oncogenes
- Precancerous Conditions
- Infiltrating Duct Carcinoma
- Intraductal Carcinoma
- Noninfiltrating Carcinoma Lobular
Publications
- Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence.| | View in PubMed
- Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.| | View in PubMed
- ASO Visual Abstract: Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy-Results from the I-SPY2 Clinical Trial.| | View in PubMed
- Clipping the Positive Lymph Node in Patients with Clinically Node Positive Breast Cancer Treated with Neoadjuvant Chemotherapy: Impact on Axillary Surgery in the ISPY-2 Clinical Trial.| | View in PubMed
- Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial.| | View in PubMed
- Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy.| | View in PubMed
- Tumor microenvironmental determinants of high-risk DCIS progression.| | View in PubMed
- Reproductive rights in the United States: acquiescence is not a strategy.| | View in PubMed
- Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.| | View in PubMed
- Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor-Positive Human Epidermal Growth Factor 2-Negative Breast Cancer.| | View in PubMed
- RE: Supplemental magnetic resonance imaging plus mammography compared with magnetic resonance imaging or mammography by extent of breast density.| | View in PubMed
- Incidence and Mitigation of Corneal Pseudomicrocysts Induced by Antibody-Drug Conjugates (ADCs).| | View in PubMed
- Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.| | View in PubMed
- 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.| | View in PubMed
- Circulating tumor cells in early lobular versus ductal breast cancer and their associations with prognosis.| | View in PubMed
- Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.| | View in PubMed
- Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery.| | View in PubMed
- Duration of Endocrine Treatment for DCIS impacts second events: Insights from a large cohort of cases at two academic medical centers.| | View in PubMed
- Characterizing attitudes related to future child-bearing in young women diagnosed with early-stage breast cancer.| | View in PubMed
- Precision Oncology in Breast Cancer Surgery.| | View in PubMed
- Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.| | View in PubMed
- Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.| | View in PubMed
- Concordance between patient-reported and physician-documented comorbidities and symptoms among Stage 4 breast cancer patients.| | View in PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB).| | View in PubMed
- Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification.| | View in PubMed
- Area Deprivation Index in Patients with Invasive Lobular Carcinoma of the Breast: Associations with Tumor Characteristics and Outcomes.| | View in PubMed
- Early Ascertainment of Breast Cancer Diagnoses Comparing Self-Reported Questionnaires and Electronic Health Record Data Warehouse: The WISDOM Study.| | View in PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database.| | View in PubMed
- Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy.| | View in PubMed
- Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment.| | View in PubMed
- A Truly Pro-Life Position Requires Access to Reproductive Health Care.| | View in PubMed
- Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial.| | View in PubMed
- Breast Conservation Surgery and Mastectomy Have Similar Locoregional Recurrence After Neoadjuvant Chemotherapy: Results From 1462 Patients on the Prospective, Randomized I-SPY2 Trial.| | View in PubMed
- Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.| | View in PubMed
- Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study.| | View in PubMed
- Prognostic Significance of Residual Ductal Carcinoma In Situ After Complete Response of Invasive Breast Cancer to Neoadjuvant Therapy-Reply.| | View in PubMed
- Development and testing of a polygenic risk score for breast cancer aggressiveness.| | View in PubMed
- Validation Study on Risk-Reduction Activities after Exposure to a Personalized Breast Cancer Risk-Assessment Education Tool in High-Risk Women in the WISDOM Study.| | View in PubMed
- Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy.| | View in PubMed
- Time to Surgery in Breast Cancer-Is Faster Always Better?| | View in PubMed
- Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.| | View in PubMed
- Guiding principles for the responsible development of artificial intelligence tools for healthcare.| | View in PubMed
- Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy.| | View in PubMed
- Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression.| | View in PubMed
- When Less Can Be More: How the 10-Year Updated Results From the Randomized Controlled AMAROS Trial Should Affect Axillary Management in the Setting of a Positive Node.| | View in PubMed
- Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes.| | View in PubMed
- Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.| | View in PubMed
- Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.| | View in PubMed
- Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer.| | View in PubMed
- Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | View in PubMed
- Association of Residual Ductal Carcinoma In Situ With Breast Cancer Recurrence in the Neoadjuvant I-SPY2 Trial.| | View in PubMed
- Informed consent process in the ISPY COVID trial is ethically acceptable.| | View in PubMed
- Focal Therapy for Prostate Cancer: Evolutionary Parallels to Breast Cancer Treatment.| | View in PubMed
- Diffusion-Weighted MRI for Predicting Pathologic Complete Response in Neoadjuvant Immunotherapy.| | View in PubMed
- Twenty-Year Benefit From Adjuvant Goserelin and Tamoxifen in Premenopausal Patients With Breast Cancer in a Controlled Randomized Clinical Trial.| | View in PubMed
- Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.| | View in PubMed
- Why It Is Time to Challenge Entrenched Beliefs About Breast Cancer Screening.| | View in PubMed
- Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | View in PubMed
- Optimizing hormone therapy for breast cancer: Translating gains to the early-stage setting.| | View in PubMed
- I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.| | View in PubMed
- Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies.| | View in PubMed
- Treatment Efficacy Score-continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials.| | View in PubMed
- Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer.| | View in PubMed
- Association of Residual Cancer Burden After Neoadjuvant Therapy and Event-Free Survival in Breast Cancer-Reply.| | View in PubMed
- Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature.| | View in PubMed
- Survivorship after neoadjuvant chemotherapy - Authors' reply.| | View in PubMed
- Evaluation of the Pathways for Survivors Program to Address Breast Cancer Survivorship-Associated Distress: Survey Study.| | View in PubMed
- Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial.| | View in PubMed
- The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.| | View in PubMed
- The incidence of discordant clinical and genomic risk in patients with invasive lobular or ductal carcinoma of the breast: a National Cancer Database Study.| | View in PubMed
- Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.| | View in PubMed
- A case-case analysis of women with breast cancer: predictors of interval vs screen-detected cancer.| | View in PubMed
- Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial.| | View in PubMed
- RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer.| | View in PubMed
- Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.| | View in PubMed
- Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST?| | View in PubMed
- Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.| | View in PubMed
- Pre-Appointment Nurse Navigation: Patient-Centered Findings From a Survey of Patients With Breast Cancer.| | View in PubMed
- Health screening needs independent regular re-evaluation.| | View in PubMed
- Trigger point injection for post-mastectomy pain: a simple intervention with high rate of long-term relief.| | View in PubMed
- The WISDOM study: a new approach to screening can and should be tested.| | View in PubMed
- The use of neoadjuvant therapy to further personalize breast cancer treatment.| | View in PubMed
- Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response.| | View in PubMed
- Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry.| | View in PubMed
- Authors' Reply: To the Letter to the Editor by Groheux et al.| | View in PubMed
- Advancing precision medicine for acute respiratory distress syndrome.| | View in PubMed
- Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial.| | View in PubMed
- Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial.| | View in PubMed
- Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies.| | View in PubMed
- PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial.| | View in PubMed
- Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial.| | View in PubMed
- Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.| | View in PubMed
- Incorporation of Patient-Reported Outcomes Measurement Information System to assess quality of life among patients with breast cancer initiating care at an academic center.| | View in PubMed
- Mask-Guided Convolutional Neural Network for Breast Tumor Prognostic Outcome Prediction on 3D DCE-MR Images.| | View in PubMed
- Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk.| | View in PubMed
- Accuracy of breast MRI in evaluating nodal status after neoadjuvant therapy in invasive lobular carcinoma.| | View in PubMed
- Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy.| | View in PubMed
- Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.| | View in PubMed
- Contralateral prophylactic mastectomy: A narrative review of the evidence and acceptability.| | View in PubMed
- A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.| | View in PubMed
- Characterization of Oligometastatic Disease in a Real-World Nationwide Cohort of 3447 Patients With de Novo Metastatic Breast Cancer.| | View in PubMed
- Accuracy of sentinel lymph node biopsy in invasive lobular carcinoma of the breast: Factors associated with false negatives.| | View in PubMed
- MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit.| | View in PubMed
- Prime Time for Consultation Audio Recordings: Supporting Shared Decision Making During and After the COVID-19 Era.| | View in PubMed
- Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.| | View in PubMed
- Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL.| | View in PubMed
- Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival.| | View in PubMed
- Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.| | View in PubMed
- Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis.| | View in PubMed
- Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | View in PubMed
- The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology.| | View in PubMed
- The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment.| | View in PubMed
- Oncological Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of the Breast: A 20-Year Institutional Experience.| | View in PubMed
- Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial.| | View in PubMed
- Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.| | View in PubMed
- Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.| | View in PubMed
- Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.| | View in PubMed
- Evaluating the impact of axillary dissection on recurrence-free survival by extent of nodal disease in invasive lobular carcinoma of the breast.| | View in PubMed
- Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater.| | View in PubMed
- Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | View in PubMed
- Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy.| | View in PubMed
- Comparison of Segmentation Methods in Assessing Background Parenchymal Enhancement as a Biomarker for Response to Neoadjuvant Therapy.| | View in PubMed
- Impact of MRI Protocol Adherence on Prediction of Pathological Complete Response in the I-SPY 2 Neoadjuvant Breast Cancer Trial.| | View in PubMed
- Tumor Sphericity Predicts Response in Neoadjuvant Chemotherapy for Invasive Breast Cancer.| | View in PubMed
- Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial.| | View in PubMed
- Personalization of Treatment is the Way Forward in Care and Trials.| | View in PubMed
- Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival.| | View in PubMed
- Response to Carter et al.| | View in PubMed
- Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).| | View in PubMed
- We need more evidence to answer questions about screening.| | View in PubMed
- Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.| | View in PubMed
- Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast.| | View in PubMed
- Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.| | View in PubMed
- A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel.| | View in PubMed
- Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer.| | View in PubMed
- Fitbit Usage in Patients With Breast Cancer Undergoing Chemotherapy.| | View in PubMed
- Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.| | View in PubMed
- Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol.| | View in PubMed
- A response to "Personalised medicine and population health: breast and ovarian cancer".| | View in PubMed
- MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.| | View in PubMed
- Should we rename low risk cancers?| | View in PubMed
- Evaluation of National Comprehensive Cancer Network guideline-based Tool for Risk Assessment for breast and ovarian Cancer (N-TRAC): A patient-reported survey for genetic high-risk assessment for breast and ovarian cancers in women.| | View in PubMed
- The WISDOM Personalized Breast Cancer Screening Trial: Simulation Study to Assess Potential Bias and Analytic Approaches.| | View in PubMed
- Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | View in PubMed
- Functional Status and Survival After Breast Cancer Surgery in Nursing Home Residents.| | View in PubMed
- Precision risk-based screening might maximize benefit and minimize harm.| | View in PubMed
- Test-retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial.| | View in PubMed
- Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.| | View in PubMed
- Diffusion-weighted MRI Findings Predict Pathologic Response in Neoadjuvant Treatment of Breast Cancer: The ACRIN 6698 Multicenter Trial.| | View in PubMed
- Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | View in PubMed
- Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.| | View in PubMed
- Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.| | View in PubMed
- Breast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 Patients.| | View in PubMed
- The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.| | View in PubMed
- Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.| | View in PubMed
- Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.| | View in PubMed
- Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.| | View in PubMed
- MRI, Clinical Examination, and Mammography for Preoperative Assessment of Residual Disease and Pathologic Complete Response After Neoadjuvant Chemotherapy for Breast Cancer: ACRIN 6657 Trial.| | View in PubMed
- Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy.| | View in PubMed
- Initial Clinical Experience With an Inducible Magnetic Seed System for Preoperative Breast Lesion Localization.| | View in PubMed
- Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction.| | View in PubMed
- Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.| | View in PubMed
- Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.| | View in PubMed
- Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.| | View in PubMed
- Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.| | View in PubMed
- The value of embedding: integrated palliative care for patients with metastatic breast cancer.| | View in PubMed
- Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.| | View in PubMed
- The WISDOM Study: breaking the deadlock in the breast cancer screening debate.| | View in PubMed
- Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.| | View in PubMed
- DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.| | View in PubMed
- Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.| | View in PubMed
- Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | View in PubMed
- Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women.| | View in PubMed
- Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | View in PubMed
- Receptor activator of nuclear factor kappa B (RANK) expression in primary breast cancer correlates with recurrence-free survival and development of bone metastases in I-SPY1 (CALGB 150007/150012; ACRIN 6657).| | View in PubMed
- Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | View in PubMed
- Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.| | View in PubMed
- Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.| | View in PubMed
- Precision surgery and avoiding over-treatment.| | View in PubMed
- Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.| | View in PubMed
- Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).| | View in PubMed
- Dedicated Breast Positron Emission Tomography for the Evaluation of Early Response to Neoadjuvant Chemotherapy in Breast Cancer.| | View in PubMed
- MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial.| | View in PubMed
- Do Prolonged Prophylactic Antibiotics Reduce the Incidence of Surgical-Site Infections in Immediate Prosthetic Breast Reconstruction?| | View in PubMed
- Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.| | View in PubMed
- Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.| | View in PubMed
- Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.| | View in PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | View in PubMed
- PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms.| | View in PubMed
- The I-SPY approach to drug development.| | View in PubMed
- Laura Esserman and Ian Thompson Discuss Strategies for Screening and Treatment of Early-Stage Cancers, and How Clinicians Can Learn From Each Other's Experiences.| | View in PubMed
- The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.| | View in PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | View in PubMed
- Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.| | View in PubMed
- When Less Is Better, but Physicians Are Afraid Not to Intervene.| | View in PubMed
- Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.| | View in PubMed
- Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.| | View in PubMed
- Population-based screening for cancer: hope and hype.| | View in PubMed
- When the Gold Standard Loses Its Luster, Perhaps It Is Time to Change Nomenclature.| | View in PubMed
- Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ-Reply.| | View in PubMed
- Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.| | View in PubMed
- A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.| | View in PubMed
- Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?| | View in PubMed
- Detection of ductal carcinoma in situ and subsequent interval cancers.| | View in PubMed
- CLINICAL DECISIONS. Ductal Carcinoma In Situ.| | View in PubMed
- Less Is More: The Evolving Surgical Approach to Breast Cancer.| | View in PubMed
- Neoadjuvant as Future for Drug Development in Breast Cancer--Response.| | View in PubMed
- The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction.| | View in PubMed
- Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation.| | View in PubMed
- Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.| | View in PubMed
- Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL.| | View in PubMed
- Rethinking the Standard for Ductal Carcinoma In Situ Treatment.| | View in PubMed
- Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer.| | View in PubMed
- Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer.| | View in PubMed
- Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.| | View in PubMed
- How to use magnetic resonance imaging following neoadjuvant chemotherapy in locally advanced breast cancer.| | View in PubMed
- Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease?| | View in PubMed
- In Regard to Hepel and Wazer.| | View in PubMed
- Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care.| | View in PubMed
- Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.| | View in PubMed
- Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management.| | View in PubMed
- Coaching patients in the use of decision and communication aids: RE-AIM evaluation of a patient support program.| | View in PubMed
- Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.| | View in PubMed
- Comparison of Mammographic Findings Following Oncoplastic Mammoplasty and Lumpectomy Without Reconstruction.| | View in PubMed
- Approaches to microvascular breast reconstruction after total skin-sparing mastectomy: a comparison of techniques.| | View in PubMed
- Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy.| | View in PubMed
- Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.| | View in PubMed
- The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction.| | View in PubMed
- The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.| | View in PubMed
- Development, implementation, and initial evaluation of a foundational open interoperability standard for oncology treatment planning and summarization.| | View in PubMed
- Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.| | View in PubMed
- Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.| | View in PubMed
- SIS.NET: a randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer.| | View in PubMed
- Expression profiling of circulating tumor cells in metastatic breast cancer.| | View in PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes.| | View in PubMed
- Aggregate cost of mammography screening in the United States.| | View in PubMed
- Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.| | View in PubMed
- Haste makes waste, but lack of urgency is opportunity lost.| | View in PubMed
- Impact of total skin-sparing mastectomy incision type on reconstructive complications following radiation therapy.| | View in PubMed
- Moving beyond the breast cancer screening debate.| | View in PubMed
- Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes.| | View in PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy in women with a history of augmentation mammaplasty: assessing the safety profile.| | View in PubMed
- Imaging features of HER2 overexpression in breast cancer: a systematic review and meta-analysis.| | View in PubMed
- Addressing overdiagnosis and overtreatment in cancer: a prescription for change.| | View in PubMed
- Fifty years of age-based screening: time for a new risk-based screening approach.| | View in PubMed
- Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657).| | View in PubMed
- Oncoplastic mammoplasty as a strategy for reducing reconstructive complications associated with postmastectomy radiation therapy.| | View in PubMed
- Patient-reported outcomes and satisfaction after total skin-sparing mastectomy and immediate expander-implant reconstruction.| | View in PubMed
- Accelerated approval for pertuzumab in the neoadjuvant setting: winds of change?| | View in PubMed
- Pretreatment vitamin D level and response to neoadjuvant chemotherapy in women with breast cancer on the I-SPY trial (CALGB 150007/150015/ACRIN6657).| | View in PubMed
- Setting a research agenda for ductal carcinoma in situ that meets the current need for change.| | View in PubMed
- Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?| | View in PubMed
- Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years.| | View in PubMed
- Making better doctors: a survey of premedical interns working as health coaches.| | View in PubMed
- Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.| | View in PubMed
- Aggregate cost of mammography screening in the United States: comparison of current practice and advocated guidelines.| | View in PubMed
- Real-Time Measurement of Functional Tumor Volume by MRI to Assess Treatment Response in Breast Cancer Neoadjuvant Clinical Trials: Validation of the Aegis SER Software Platform.| | View in PubMed
- Mammographic screening detects low-risk tumor biology breast cancers.| | View in PubMed
- Development of a personalized decision aid for breast cancer risk reduction and management.| | View in PubMed
- Changing the terminology of cancer--reply.| | View in PubMed
- Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.| | View in PubMed
- Evolving paradigm for imaging, diagnosis, and management of DCIS.| | View in PubMed
- Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery.| | View in PubMed
- Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.| | View in PubMed
- Screening: biology dictates the fate of young women with breast cancer.| | View in PubMed
- The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.| | View in PubMed
- Impact of ductal carcinoma in situ terminology on patient treatment preferences.| | View in PubMed
- Overdiagnosis and overtreatment in cancer: an opportunity for improvement.| | View in PubMed
- Total skin-sparing mastectomy in BRCA mutation carriers.| | View in PubMed
- The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care.| | View in PubMed
- Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer.| | View in PubMed
- Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | View in PubMed
- Feasibility of Performing Total Skin-Sparing Mastectomy in Patients With Prior Circumareolar Mastopexy or Reduction Mammoplasty Incisions.| | View in PubMed
- Reducing false-positive biopsies: a pilot study to reduce benign biopsy rates for BI-RADS 4A/B assessments through testing risk stratification and new thresholds for intervention.| | View in PubMed
- Recognising the benefits and harms of breast cancer screening: an opportunity to target improvement.| | View in PubMed
- Total skin-sparing mastectomy: a systematic review of oncologic outcomes and postoperative complications.| | View in PubMed
- Developing safety criteria for introducing new agents into neoadjuvant trials.| | View in PubMed
- Reply: The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy.| | View in PubMed
- An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.| | View in PubMed
- Physician behaviors surrounding the implementation of decision and communication AIDS in a breast cancer clinic: a qualitative analysis of staff intern perceptions.| | View in PubMed
- Will early detection for breast cancer ever work?| | View in PubMed
- Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.| | View in PubMed
- Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.| | View in PubMed
- Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.| | View in PubMed
- Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.| | View in PubMed
- Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors.| | View in PubMed
- Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure.| | View in PubMed
- Breast cancer screening: the questions answered.| | View in PubMed
- The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors.| | View in PubMed
- Adoption, acceptability, and accuracy of an online clinical trial matching website for breast cancer.| | View in PubMed
- Biology of breast cancer in Nigerian women: a pilot study.| | View in PubMed
- Whole-genome analysis informs breast cancer response to aromatase inhibition.| | View in PubMed
- A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.| | View in PubMed
- Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.| | View in PubMed
- Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL.| | View in PubMed
- The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study.| | View in PubMed
- Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.| | View in PubMed
- Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.| | View in PubMed
- Breast cancer recurrence is dictated by high-risk biology, not choice of surgery.| | View in PubMed
- Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts.| | View in PubMed
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.| | View in PubMed
- Overdiagnosis and overtreatment of breast cancer.| | View in PubMed
- Targeting Molecular Aberrations in Breast Cancer: Is It about Time?| | View in PubMed
- Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | View in PubMed
- Accelerating identification and regulatory approval of investigational cancer drugs.| | View in PubMed
- Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types.| | View in PubMed
- Impact of mammographic screening on the detection of good and poor prognosis breast cancers.| | View in PubMed
- Outcome of long term active surveillance for estrogen receptor-positive ductal carcinoma in situ.| | View in PubMed
- Leukocyte composition of human breast cancer.| | View in PubMed
- Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN 6657, InterSPORE Trial).| | View in PubMed
- Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.| | View in PubMed
- Biologic markers determine both the risk and the timing of recurrence in breast cancer.| | View in PubMed
- A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.| | View in PubMed
- Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int| | View in PubMed
- Characterizing the impact of 25 years of DCIS treatment.| | View in PubMed
- The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ.| | View in PubMed
- Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.| | View in PubMed
- A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.| | View in PubMed
- The Communication and Care Plan: a novel approach to patient-centered clinical information systems.| | View in PubMed
- Long-term prognostic role of functional limitations among women with breast cancer.| | View in PubMed
- Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.| | View in PubMed
- Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience.| | View in PubMed
- Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction.| | View in PubMed
- Lessons learned from genetic testing.| | View in PubMed
- Expanding the reach of decision and communication aids in a breast care center: a quality improvement study.| | View in PubMed
- Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.| | View in PubMed
- Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins?| | View in PubMed
- Solving the overdiagnosis dilemma.| | View in PubMed
- Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.| | View in PubMed
- Application of screening principles to the reconstructed breast.| | View in PubMed
- Rethinking screening for breast cancer and prostate cancer.| | View in PubMed
- Bacteriologic features of surgical site infections following breast surgery.| | View in PubMed
- Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.| | View in PubMed
- A comparison of RNA amplification techniques at sub-nanogram input concentration.| | View in PubMed
- I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.| | View in PubMed
- Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.| | View in PubMed
- Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.| | View in PubMed
- Oncologist use of the Adjuvant! model for risk communication: a pilot study examining patient knowledge of 10-year prognosis.| | View in PubMed
- The UCSC Cancer Genomics Browser.| | View in PubMed
- Hypertension is an independent predictor of survival disparity between African-American and white breast cancer patients.| | View in PubMed
- Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients.| | View in PubMed
- When informed, all women do not prefer breast conservation.| | View in PubMed
- Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model.| | View in PubMed
- Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.| | View in PubMed
- Converting evidence to practice: a guide for the clinical application of MRI for the screening and management of breast cancer.| | View in PubMed
- Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer?| | View in PubMed
- Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center.| | View in PubMed
- Invasive breast cancer: predicting disease recurrence by using high-spatial-resolution signal enhancement ratio imaging.| | View in PubMed
- Risk communication with patients with breast cancer: cautionary notes about printing Adjuvant! estimates.| | View in PubMed
- Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.| | View in PubMed
- Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference.| | View in PubMed
- Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.| | View in PubMed
- Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning.| | View in PubMed
- Optimizing the total skin-sparing mastectomy.| | View in PubMed
- A role for biomarkers in the screening and diagnosis of breast cancer in younger women.| | View in PubMed
- Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer.| | View in PubMed
- Fluorescence in situ hybridization of ductal lavage samples identifies malignant phenotypes from cytologically normal cells in women with breast cancer.| | View in PubMed
- Pilot trial of a computerized decision aid for breast cancer prevention.| | View in PubMed
- Ductal carcinoma in situ in BRCA mutation carriers.| | View in PubMed
- Analysis of molecular inversion probe performance for allele copy number determination.| | View in PubMed
- Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.| | View in PubMed
- Type and duration of exogenous hormone use affects breast cancer histology.| | View in PubMed
- Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ.| | View in PubMed
- Magnetic resonance imaging captures the biology of ductal carcinoma in situ.| | View in PubMed
- Breast cancer growth prevention by statins.| | View in PubMed
- Evaluation of a visit preparation intervention implemented in two rural, underserved counties of Northern California.| | View in PubMed
- Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice.| | View in PubMed
- Clinical trials are required to prove the chemopreventive worth of statins.| | View in PubMed
- A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.| | View in PubMed
- Mammographic, sonographic, and pathologic characteristics of Burkitt's lymphoma in a patient referred for diagnostic mammography.| | View in PubMed
- Breast cancer risk assessment and prevention: a framework for shared decision-making consultations.| | View in PubMed
- Genetic/familial high-risk assessment: breast and ovarian.| | View in PubMed
- Statins: health-promoting agents show promise for breast cancer prevention.| | View in PubMed
- Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.| | View in PubMed
- Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.| | View in PubMed
- Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.| | View in PubMed
- The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer.| | View in PubMed
- Ratio of positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients.| | View in PubMed
- MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.| | View in PubMed
- Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.| | View in PubMed
- Immune dysfunction and micrometastases in women with breast cancer.| | View in PubMed
- Integration of imaging in the management of breast cancer.| | View in PubMed
- Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans.| | View in PubMed
- Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease.| | View in PubMed
- Internal mammary sentinel lymph node mapping for invasive breast cancer: implications for staging and treatment.| | View in PubMed
- Recruitment, genetic counseling, and BRCA testing for underserved women at a public hospital.| | View in PubMed
- Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation.| | View in PubMed
- Evaluation of breast cancer risk assessment techniques: a cost-effectiveness analysis.| | View in PubMed
- Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.| | View in PubMed
- Applying the neoadjuvant paradigm to ductal carcinoma in situ.| | View in PubMed
- Neoadjuvant chemotherapy for primary breast cancer: lessons learned and opportunities to optimize therapy.| | View in PubMed
- Neoadjuvant hormonal therapy for ductal carcinoma in situ: trial design and preliminary results.| | View in PubMed
- An XML message broker framework for exchange and integration of microarray data.| | View in PubMed
- Racial differences in mammographic breast density.| | View in PubMed
- Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium.| | View in PubMed
- Magnetic resonance imaging in patients diagnosed with ductal carcinoma-in-situ: value in the diagnosis of residual disease, occult invasion, and multicentricity.| | View in PubMed
- MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?| | View in PubMed
- Failure to harvest sentinel lymph nodes identified by preoperative lymphoscintigraphy in breast cancer patients.| | View in PubMed
- Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions.| | View in PubMed
- Improving the quality of decision making in breast cancer: consultation planning template and consultation recording template.| | View in PubMed
- Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy.| | View in PubMed
- Axillary metastasis from a malignant mullerian mixed tumor.| | View in PubMed
- Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers.| | View in PubMed
- Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.| | View in PubMed
- Consultation planning to help breast cancer patients prepare for medical consultations: effect on communication and satisfaction for patients and physicians.| | View in PubMed
- Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.| | View in PubMed
- Magnetic resonance imaging for primary breast cancer management: current role and new applications.| | View in PubMed
- Skin-sparing mastectomy and immediate breast reconstruction: a prospective cohort study for the treatment of advanced stages of breast carcinoma.| | View in PubMed
- New approaches to the imaging, diagnosis, and biopsy of breast lesions.| | View in PubMed
- Improving the accuracy of mammography: volume and outcome relationships.| | View in PubMed
- Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.| | View in PubMed
- Does timely assessment affect the anxiety associated with an abnormal mammogram result?| | View in PubMed
- MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer.| | View in PubMed
- The impact of alternative practices on the cost and quality of mammographic screening in the United States.| | View in PubMed
- Ductal growth is impeded in mammary glands of C-neu transgenic mice.| | View in PubMed
- MR imaging of the breast in patients with positive margins after lumpectomy: influence of the time interval between lumpectomy and MR imaging.| | View in PubMed
- Integration of breast imaging into cancer management.| | View in PubMed
- Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability.| | View in PubMed
- Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.| | View in PubMed
- Building bridges between physicians and patients: results of a pilot study examining new tools for collaborative decision making in breast cancer.| | View in PubMed
- Management of ductal carcinoma in situ.| | View in PubMed
- Biological therapies for breast carcinoma: concepts for improvement in survival.| | View in PubMed
- Prophylactic mastectomy in women with a high risk of breast cancer.| | View in PubMed
- Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.| | View in PubMed
- Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor Histopathology and Angiogenesis in Breast Carcinoma.| | View in PubMed
- Utility of magnetic resonance imaging in the management of breast cancer: evidence for improved preoperative staging.| | View in PubMed
- A multicenter randomized trial of DIAC for cyclical mastopathy.| | View in PubMed
- Is routine frozen section assessment feasible in the practice environment of the 1990s?| | View in PubMed
- Hormone replacement therapy and breast cancer risk.| | View in PubMed
- Ultrasound tissue characterization of breast biopsy specimens: expanded study.| | View in PubMed
- Barriers to care and treatment: the challenge of daily radiation therapy.| | View in PubMed
- Should we recommend screening mammography for women aged 40 to 49?| | View in PubMed
- Breast.| | View in PubMed
- Trade-offs between survival and breast preservation for three initial treatments of ductal carcinoma-in-situ of the breast.| | View in PubMed
- Potentially ineffective care. A new outcome to assess the limits of critical care.| | View in PubMed
- Cost per anomaly: what does a diaphragmatic hernia cost?| | View in PubMed
- An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site.| | View in PubMed
- Follicular lymphoma: a model of lymphoid tumor progression in man.| | View in PubMed
- Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.| | View in PubMed
- Development of a new therapeutic approach to B cell malignancy. The induction of immunity by the host against cell surface receptor on the tumor.| | View in PubMed
- Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide.| | View in PubMed
- Myocardial performance and extracellular ionized calcium in a severely failing human heart.| | View in PubMed
- A novel method for emergency immobilization of the wrist during cross-country skiing.| | View in PubMed